abstract：:Working people who are diagnosed with cancer must generally stop working, and returning to work after treatment is a very important issue for them. This article investigates the impact of cancer on professional trajectory among working women after a breast cancer diagnosis. We conducted in-depth interviews with 21 wom...

journal_title：Bulletin du cancer

authors： Gallardo L,Rey D,Peretti-Watel P

更新日期：2012-07-01 00:00:00

abstract：:Despite development and widespread of PSA, current tools evaluating prostate cancer still give inconsistent or insufficiently relevant results. As encouraging data raised from circulating tumor cells detection in colon or breast cancer, they were evaluated as a surrogate prostate cancer biomarker. Tumor cells need to ...

journal_title：Bulletin du cancer

authors： Murez T,Droupy S,Rebillard X,Alix-Panabieres C

更新日期：2012-07-01 00:00:00

abstract：:Combination of radiotherapy and androgen deprivation is now considered as the standard of care for patients with a localized prostate cancer but poor prognostic factors. Two groups of randomized trials have led to this recommendation. Some have compared radiotherapy alone versus hormonal treatment and radiotherapy: th...

journal_title：Bulletin du cancer

authors： Quero L,Wong-Hee-Kam S,Rivera S,Hennequin C

更新日期：2012-07-01 00:00:00

abstract：:The treatment of metastatic melanoma is presently in complete revolution. Two molecules have recently been authorized for this indication. These treatments have a very different mechanism of action compared to previous chemotherapies. Vemurafenib is a targeted therapy, which blocks BRAF selectively. This molecule indu...

journal_title：Bulletin du cancer

authors： Mateus C,Robert C

更新日期：2012-06-01 00:00:00

abstract：:Breast cancer (BC) has the highest incidence rate in women in industrialized countries. Statistically, it is estimated that one out of 10 women will develop BC during her life. Evidence is accumulating for the role of ion channels in the development of cancer. Most studied ion channels in BC are K(+) channels, which a...

journal_title：Bulletin du cancer

authors： Ouadid-Ahidouch H,Dhennin-Duthille I,Gautier M,Sevestre H,Ahidouch A

更新日期：2012-06-01 00:00:00

abstract：:Pain is frequent in cancer patients. To date, there is a consequent therapeutic arsenal so to manage pain; the different treatment strategies are the subject of various recommendations. Patients with cancer also frequently suffer from renal insufficiency, and this comorbidity may disrupt or jeopardize the analgesic st...

journal_title：Bulletin du cancer

authors： Rey JB,Tran T,Ammar D,Parent D,Janus N,Launay-Vacher V

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND AND AIM:CABYR, a calcium-binding tyrosine phosphorylation regulated fibrous sheath protein, was initially reported to be testis-specific and subsequently shown to be present in brain tumors, pancreas cancer and lung cancer. This study aimed to investigate the expression and effects of the CABYR-c transcript ...

journal_title：Bulletin du cancer

authors： Li H,Fang L,Xiao X,Shen L

更新日期：2012-03-01 00:00:00

abstract：:Cancer patients frequently undergo imaging examinations to diagnosis but also to evaluate their responses to treatment. These patients are also at high risk of kidney impairment before considering the possible nephrotoxicity of their chemotherapy. In this context, it is overriding to know contrast agents induced risks...

journal_title：Bulletin du cancer

authors： Amet S,Deray G

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:A high prevalence of renal insufficiency has been observed in cancer patients as well as a high incidence of de novo cancer in dialysis or renal transplant patients. MATERIAL AND METHODS:We aimed to determine the incidence of cancer in patients under dialysis and in kidney transplant recipients through a se...

journal_title：Bulletin du cancer

authors： Janus N,Launay-Vacher V,Ferrero JM,Thariat J

更新日期：2012-03-01 00:00:00

abstract：:Patients wish to be fully informed about their health, but some information and its disclosure may pose special challenges depending on the severity of the illness. This prospective observational study investigates the content of information about the disease and treatment, as well as the process by which information ...

journal_title：Bulletin du cancer

authors： Marcoux I

更新日期：2012-02-01 00:00:00

abstract：:Protein phosphorylation is a fundamental post-translational modification. It regulates a large number of critical cellular processes (differentiation, division, proliferation, apoptosis). Cell division is a process including a series of phases by which a parent cell divides into two daughter cells. The cells enter the...

journal_title：Bulletin du cancer

authors： Carassou P,Meijer L,Le Moulec S,Aoun J,Bengrine-Lefèvre L

更新日期：2012-02-01 00:00:00

abstract：:In Europe, renal tumours are 7th in frequency of men cancers. They are rare tumours in 10 to 15% of cases. Collecting ducts carcinomas or Bellini tumours, described for the first time in 1949, are a distinct clinical and pathological entity. They represented 1% of epithelial cancers. Nephrectomy is the treatment of lo...

journal_title：Bulletin du cancer

authors： Teghom C,Gachet J,Scotté F,Elaidi R,Oudard S

更新日期：2011-10-01 00:00:00

abstract：:To assess the effectiveness of a standardized form in altering family physicians knowledge regarding supportive care delivered to their patients. We conducted an uncontrolled before and after study involving 42 cancer patients who were provided with supportive care at hospital. During the intervention study period, a ...

journal_title：Bulletin du cancer

authors： Fouquereau J,Laval G,Labarère J

更新日期：2011-10-01 00:00:00

abstract：:Cytogenetic, molecular and phenotyping features of malignant hematologic diseases succeeded in improving their management by a more accurate stratification of patients according to several groups of risk and by providing a rational for targeted therapy. Three major types of treatment (excluding cellular therapy) are c...

journal_title：Bulletin du cancer

authors： Baleydier F,Domenech C,Thomas X

更新日期：2011-08-01 00:00:00

abstract：:IMiDs belong to a new pharmalogical class, whose principal therapeutic agents are the thalidomide and the lenalidomide. They have immunomodulatory and antiangiogenic properties, as well as a direct effect on tumor cells. Thalidomide and lenalidomide were first approved for multiple myeloma, and in 5q-myelodysplastic s...

journal_title：Bulletin du cancer

authors： Wémeau M,Gauthier J,Leleu X,Yakoub-Agha I

更新日期：2011-08-01 00:00:00

abstract：:Allogeneic hematopoietic stem cell transplantation (HSCT) is the treatment of choice of hematologic malignancies. Acute graft versus host disease (GvHD) is common after HSCT and directly related to graft versus leukemia effect. Little progress has been done in the treatment of acute GvHD. The first line treatment is u...

journal_title：Bulletin du cancer

authors： Xhaard A,Hermet E,Bay JO,Peffault de Latour R

更新日期：2011-08-01 00:00:00

abstract：:Distinct clinicopathologic acute lymphoblastic leukemia (ALL) entities have been identified, resulting in the adoption of risk-oriented treatment approaches. In Philadelphia chromosome-positive (Ph(+)) ALL, the optimal treatment requires the addition of BCR-ABL tyrosine kinase inhibitors, as imatinib. However, the out...

journal_title：Bulletin du cancer

authors： Thomas X

更新日期：2011-07-01 00:00:00

abstract：:This survey, conducted in region Rhône-Alpes (France), aims to assess some data in thoracic oncology practice including availability of specialized equipments. This study is based on a questionnaire mailed to oncologists and pulmonologists in the region. Of 401 questionnaires, the response rate was 56%. Responses of 7...

journal_title：Bulletin du cancer

authors： Couraud S,Fournel P,Moro-Sibilot D,Pérol M,Souquet PJ

更新日期：2011-06-09 00:00:00

abstract：:Neuroblastoma is the most common pediatric extracranial solid cancer. Patients with metastatic disease at initial diagnosis who are greater than 18  months of age and patients with MycN amplified locoregional tumors are treated with intensive multimodal therapy. While this intensive approach has been shown to improve ...

journal_title：Bulletin du cancer

authors： Défachelles AS,Cougnenc O,Carpentier P

更新日期：2011-05-01 00:00:00

abstract：:Whole brain radiotherapy remains standard in the management of breast cancer patients with brain metastases. It allows for symptomatic improvement and good local control in most patients. However, its results remain suboptimal in terms of both efficacy and toxicity. In highly selected patients, stereotactic radiothera...

journal_title：Bulletin du cancer

authors： Kirova YM,Chargari C,Mazeron JJ

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Depression is an important symptom for many palliative care patients but is rarely identified. It's known to reduce quality of life and impact on palliation of physical symptom. These physical symptoms can be improved by an adequate treatment of depression. Many depressed cancer patients are not treated due ...

journal_title：Bulletin du cancer

authors： Rhondali W,Perceau E,Saltel P,Girard R,Filbet M

更新日期：2011-02-01 00:00:00

abstract：:Since premedication of patients with an H1 antihistamine is recommended before the start of the intravenous infusion of temsirolimus, temsirolimus is to be used with caution in cases where there is a history of hypersensitivity to this class of antihistamines, or medical contra-indication for treatment with antihistam...

journal_title：Bulletin du cancer

authors： Massard C,Patard JJ,Hermine O,Ravaud A

更新日期：2011-01-01 00:00:00

abstract：:Perioperative chemotherapy for gastric cancer is validated by two phase III studies. The impact of the preoperative neoadjuvant sequence is probably major in the benefit of this treatment. This chemotherapy increases the R0 resection without increasing either morbidity or mortality. Furthermore, it reduces local and s...

journal_title：Bulletin du cancer

authors： Flamein R,Antomarchi O,Pezet D

更新日期：2011-01-01 00:00:00

abstract：:Recommendations for the management of gastrointestinal stromal tumours (GIST) in children and adolescents do presently not exist. Thus, a summary of the current literature was conducted serving as a basis for the development of optimal management strategies for childhood GIST. Pediatric cases of GIST may occur sporadi...

journal_title：Bulletin du cancer

authors： Verschuur A,André N,Blay JY

更新日期：2011-01-01 00:00:00

abstract：:The congress of Asco made the object of numerous summaries of congress made in the heat of the moment and the Bulletin du Cancer decided to ask to his editorial board, a digested summary, at distance of the congress, to try to sum up the data of the congress which are going to change practice. Of the considerable numb...

journal_title：Bulletin du cancer

authors： André T,Wislez M,Goncalves A,de La Motte Rouge T,Blay JY,Massard C,Bay JO,comité de rédaction du Bulletin du Cancer.

更新日期：2010-12-01 00:00:00

abstract：:The discovery of oncogenes and tumor suppressors has established the original concept of cancer development based on a cascade of spontaneously occurring somatic mutations. It is now well known that genomes of cancer cells are deeply rearranged and that these rearrangements have devastating consequences on their organ...

journal_title：Bulletin du cancer

authors： Theillet C

更新日期：2010-11-01 00:00:00

abstract：:Genomic DNA displays a non canonical structure prone to be damaged and modified by genotoxic stresses, which are induced either by the endogenous metabolism or attacks from environment or therapeutic pressure. Several molecular pathways allow cells to repair such DNA lesions. Additional mechanisms have been selected t...

journal_title：Bulletin du cancer

authors： Cazaux C

更新日期：2010-11-01 00:00:00

abstract：:Cell signalling represents the network of cell communication pathways. Reception of a message by a cell results in the implementation of various direct and indirect actions, especially through the transcription of the genes required for carrying out the orders received. The signals exchanged by cells may concern proli...

journal_title：Bulletin du cancer

authors： Robert J

更新日期：2010-11-01 00:00:00

abstract：:Recent progress in the field of molecular biology has allowed us to identify at least two different molecular mechanisms implicated in colorectal carcinogenesis (CRC): chromosomal instability (CIN) and genetic instability. Even though the two molecular mechanisms differ, their signalling pathways, implicated in malign...

journal_title：Bulletin du cancer

authors： Laurent-Puig P,Agostini J,Maley K

更新日期：2010-11-01 00:00:00

abstract：:Announcing a cancer diagnosis, but also a relapse, a progression of the disease, or transition towards palliative care constitute particularly difficult communication issues for the patient as well as for the clinician, during the trajectory of care. The objectives of this article is to present the clinical stakes of ...

journal_title：Bulletin du cancer

authors： Dolbeault S,Brédart A

更新日期：2010-10-01 00:00:00

abstract：:In recent years, Internet has become an indispensable tool for all types of information. Its importance has increased in medicine and particularly in human malignancies. The data issued by the Internet are many and varied sources ranging from official websites to patient's blogs. HIV infection is an infection highly p...

journal_title：Bulletin du cancer

authors： Cluzeau T,Mounier N

更新日期：2010-10-01 00:00:00

abstract：:Stereotactic radiation therapy, consisting in irradiating the tumor with a high dose per fraction, has a therapeutic potential because of excellent local control. This technique requires a high accuracy level in order to minimize the risk of normal tissue toxicity. Initially used for cerebral localization, the stereot...

journal_title：Bulletin du cancer

authors： Ayadi M,Ginestet C,Gassa F,Claude L,Mazeron JJ

更新日期：2010-07-01 00:00:00

abstract：:With over 70,000 patients treated worldwide, protontherapy has an evolution on their clinical applications and technological developments. The ballistic advantage of the Bragg peak gives the possibility of getting a high conformation of the dose distribution to the target volume. Protontherapy has accumulated a consid...

journal_title：Bulletin du cancer

authors： Mazal A,Habrand JL,Delacroix S,Datchary J,Dendale R,Desjardins L,Ferrand R,Malka V,Fourquet A

更新日期：2010-07-01 00:00:00

abstract：:Carbon ion therapy is an innovative radiation therapy. It has been first proposed in the forties by Robert Wilson, however the first dedicated centres for human care have been build up only recently in Japan and Germany. The interest of carbon ion is twofold: 1) the very sharp targeting of the tumour with the so calle...

journal_title：Bulletin du cancer

authors： Pommier P,Hu Y,Baron MH,Chapet O,Balosso J

更新日期：2010-07-01 00:00:00

abstract：:Image guided radiation therapy (IGRT) is a major technical innovation of radiotherapy. It allows locating the tumor under the linear accelerator just before the irradiation, by direct visualization (3D mode soft tissue) or indirect visualization (2D mode and radio-opaque markers). The technical implementation of IGRT ...

journal_title：Bulletin du cancer

authors： Lagrange JL,de Crevoisier R

更新日期：2010-07-01 00:00:00

abstract：:Ewing tumours are characterised as tumours consisting of small, blue, round malignant cells that may exhibit varying degrees of neural differentiation. Most of them arise in bony sites, and they represent the second commonest primary osseous malignancy in and adolescence and young adults. During the past 30 years, che...

journal_title：Bulletin du cancer

authors： Marec-Bérard P,Chotel F,Claude L

更新日期：2010-06-01 00:00:00

abstract：:The radiobiological properties of the hadrons (neutrons, protons, carbon ions) led to their therapeutic use in sarcomas, as a referent therapy or as an alternative to photon therapy. An extensive review of the literature has been conducted to assess the present indications and the perspectives for hadrontherapy. Compa...

journal_title：Bulletin du cancer

authors： Pommier P,Sunyach MP,Hu Y,Amsalem E,Claude L,Moncort-Boulch D,Toutenu P,Balosso J

更新日期：2010-06-01 00:00:00

abstract：:We report the results of the protocol CMA (cyclophosphamide, methotrexate, Aracytine) reinforced of 26 patients affected by Burkitt lymphoma in facial-maxillary localisation, in a retrospective study from January 2000 till December 2007 and prospective from January till September 2008. Their average age was 7.89 years...

journal_title：Bulletin du cancer

authors： Tolo-Diebkilé A,Koffi GK,Nanho CD,Sawadogo D,Kouakou B,Siransi-Bogui L,Ayémou R,Sanogo I

更新日期：2010-05-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) represents one of the most frequent epithelial tumours of the child in intermediate risk regions. In the Maghreb, it represents the first cancer of teenagers of 15-20 years old. The Epstein Barr virus (EBV) is the most important etiologic factor. Its role in the pathogeneses of NPC has b...

journal_title：Bulletin du cancer

authors： Toumi N,Frikha M,Siala W,Khabir A,Karray H,Boudawara T,Gargouri RM,Ghorbel M,Daoud J

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To assess the feasibility and efficacy of cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) without adjuvant chemotherapy for relapsed or persistent advanced ovarian cancer. METHODS:This observational study included stage IIIC ovarian cancer patients due to undergo CRS...

journal_title：Bulletin du cancer

authors： Carrabin N,Mithieux F,Meeus P,Trédan O,Guastalla JP,Bachelot T,Labidi SI,Treilleux I,Rivoire M,Ray-Coquard I

更新日期：2010-04-01 00:00:00